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Neurotransmitter Balancing During Benzo Withdrawal

We think many individuals can benefit from targeted amino acid therapy during a medication withdrawal. It helps control certain symptoms.


The human brain consists of billions of cells that communicate through the use of different molecules. Neurotransmitters are types of molecules that send particular messages from one nerve cell to another. They are made in the nerve cells and released into the synapse, the gap between nerve cells, where they are picked up by adjacent neurons. These neurotransmitters target specific areas, called receptors on the next nerve cell,  initiating a particular response in that neuron. This collective response, at the cellular level, is reflected in our moods and reactions to the environment. The correct balance of these neurotransmitter molecules is an important part of optimal brain function.

What are Neurotransmitters?

There are dozens of different types of neurotransmitters, and each creates a unique response, leading to specific effects on brain function. Here are examples of neurotransmitters:


  1. Serotonin: Regulates our mood and sleep, and other functions related to well-being.

  2. Dopamine: Plays a role in motivation, reward, movement, and emotional regulation.

  3. Glutamate: the most abundant neurotransmitter in the brain.  acts as an excitatory neurotransmitter, thereby facilitating the transmission of signals in the brain.  Involved in learning and memory. Balances GABA signaling.

  4. Gamma-aminobutyric acid (GABA): the second most abundant neurotransmitter in the brain. Acts as an inhibitory neurotransmitter-reduces neuronal activity, and promotes relaxation. Balances glutamate signaling

  5. Endorphins- our natural opiate in the brain


While neurotransmitters are most commonly associated with brain function, they are also involved in the regulation of numerous other processes in the body. For example, serotonin and dopamine are also found in the gastrointestinal tract, where they participate in regulating digestion and other gut functions.

How are neurotransmitters made?
The synthesis of each neurotransmitter requires specific amino acids, enzymes, and cofactors. If each of these components is not present in sufficient quantity, the nerve cells cannot manufacture enough neurotransmitters for good brain function, and the stores of these are depleted. Eventually, symptoms of depression, anxiety, irritability, insomnia, etc., can occur.


The use of benzodiazepines can have multiple, known and unknown effects on the brain. We know benzodiazepines have direct effects on the GABA receptor and ion channels. Affecting one neurotransmitter can affect all the other neurotransmitters and hormones, as they all exist in balance with each other.


What are amino acids?

Amino acids are nutrients derived from proteins. They are utilized by the brain to generate key neurotransmitters. There are 20 different amino acids, and 9 are essential that we need to get from our food intake. Often our diets are not adequate, because of poor appetite or digestion and absorption issues in the gut. A deficiency in amino acids can lead to poor brain function.

For example, the use of the amino acid Tyrosine for the appropriate individual can increase the neurotransmitters dopamine, epinephrine, and norepinephrine.

Why use amino acids for neurotransmitter repletion?

Brain-targeted amino acid supplementation offers numerous benefits and advantages while tapering. Numerous published studies in peer review journals have shown that targeted therapy can increase mood and well-being. We evaluate symptoms that an individual may be experiencing with the neurotransmitter depletion questionnaire indicating a particular imbalance.  Focusing on supplying amino acids that support neurotransmitter function can yield significant positive outcomes. It is important to note that individual responses to supplementation may vary, and needs to be used in coordination with a healthcare professional.


In summary, brain-targeted amino acid supplementation provides a range of benefits, including enhanced neurotransmitter production, optimal brain performance, neuroprotection, improved mood and stress management, and support for brain health throughout life. By nourishing the brain with essential amino acids, individuals can potentially optimize their cognitive abilities and overall well-being.

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